According to a recent study, more than 2 percent of the US population can't play video games due to poor accessibility options. This same study suggests more than 9 percent are unable to enjoy the traditional gaming experience because of visual, cognitive, or physical impairments. Additional research suggests 20 percent of the casual gaming audience is disabled in some fashion.
That amounts to millions of disabled players who are locked out of games because of a lack of support. But after decades in which accessibility options were absent or an afterthought, game developers in recent years have shown an increasing willingness to cater to this audience explicitly.
See How game makers are catering to disabled players
Hardware and software solutions open gaming to a wider audience than ever.